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Development of ketobenzothiazole-based peptidomimetic TMPRSS13 inhibitors with low nanomolar potency

TMPRSS13, a member of the Type II Transmembrane Serine Proteases (TTSP) family, is involved in cancer progression and in respiratory virus cell entry. To date, no inhibitors have been specifically developed for this protease. In this study, a chemical library of 65 ketobenzothiazole-based peptidomim...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Alexandre Joushomme, Antoine Désilets, William Champagne, Malihe Hassanzadeh, Gabriel Lemieux, Alice Gravel-Trudeau, Matthieu Lepage, Sabrina Lafrenière, Ulrike Froehlich, Karin List, Pierre-Luc Boudreault, Richard Leduc
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis Group 2025-12-01
Saila:Journal of Enzyme Inhibition and Medicinal Chemistry
Gaiak:
Sarrera elektronikoa:https://www.tandfonline.com/doi/10.1080/14756366.2025.2466841
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