TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells
The spike protein S of SARS-CoV-2 is activated by TMPRSS2 and furin. Inhibition of either one of these proteases can render the S protein unable to mediate virus entry and, therefore, provides a promising approach for COVID-19 treatment. The novel emerged SARS-CoV-2 has rapidly spread around the wor...
Furkejuvvon:
| Váldodahkkit: | , , , , , , , , , , , , , , |
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| Materiálatiipa: | Artigo |
| Giella: | Inglês |
| Almmustuhtton: |
Life Science Alliance LLC
2020-09-01
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| Ráidu: | Life Science Alliance |
| Liŋkkat: | https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202000786 |
| Fáddágilkorat: |
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