High-parameter phenotypic characterization reveals a subset of human Th17 cells that preferentially produce IL-17 against M. tuberculosis antigen

BackgroundInterleukin-17–producing CD4 T cells contribute to the control of Mycobacterium tuberculosis (Mtb) infection in humans; whether infection with human immunodeficiency virus (HIV) disproportionately affects distinct Th17-cell subsets that respond to Mtb is incompletely defined.MethodsWe perf...

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Autors principals:	Paul Ogongo, Anthony Tran, Florence Marzan, David Gingrich, Melissa Krone, Francesca Aweeka, Cecilia S. Lindestam Arlehamn, Jeffrey N. Martin, Steven G. Deeks, Peter W. Hunt, Joel D. Ernst
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2024-04-01
Col·lecció:	Frontiers in Immunology
Matèries:	interleukin-17 CD4 T-cells antigen-responsive immunity tuberculosis ART-suppressed
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1378040/full
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