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A Mycobacterium tuberculosis rare variable antigen vaccine reduces lung pathology in hypersusceptible SP140−/− mice

Mycobacterium tuberculosis is the leading cause of death globally due to a single infectious agent. Currently, no licensed vaccine protects against pulmonary tuberculosis, the primary adult disease caused by Mtb infection. CD4 T cells are essential in protection against Mtb infection and inducing a...

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Uloženo v:
Hlavní autoři: Zachary P. Howard, Alexander Mohapatra, Weihao Zheng, Joel D. Ernst
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2026-07-01
Edice:Frontiers in Tuberculosis
Témata:
antigens
CD4 T cells
epitopes
mycobacterium tuberculosis
prevention-of-disease
vaccine
On-line přístup:https://www.frontiersin.org/articles/10.3389/ftubr.2026.1814646/full
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