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Species-specific alternative splicing of SP110 drives tuberculosis susceptibility in cattle

Abstract Bovine tuberculosis (bTB) is a chronic debilitating zoonotic disease caused by Mycobacterium bovis (M. bovis). M. bovis exhibits a broad host range, but dairy cattle are particularly susceptible. The SP110 (speckled protein 110) gene has been demonstrated to be associated with host suscepti...

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Principais autores: Ajiao Fan, Ying Guo, Zhunan Li, Xiangchen Dong, Zihan Zhang, Xinyu Wang, Yanliang Song, Jing Han, Jing Yang, Haoxin Wang, Xinyan Zhang, Yong Zhang, Yuanpeng Gao
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-12-01
Serier:Veterinary Research
Fag:
Dairy cows
Mycobacterium tuberculosis
SP110
alternative splicing
Online adgang:https://doi.org/10.1186/s13567-025-01644-3
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