Species-specific alternative splicing of SP110 drives tuberculosis susceptibility in cattle

Abstract Bovine tuberculosis (bTB) is a chronic debilitating zoonotic disease caused by Mycobacterium bovis (M. bovis). M. bovis exhibits a broad host range, but dairy cattle are particularly susceptible. The SP110 (speckled protein 110) gene has been demonstrated to be associated with host suscepti...

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Principais autores:	Ajiao Fan, Ying Guo, Zhunan Li, Xiangchen Dong, Zihan Zhang, Xinyu Wang, Yanliang Song, Jing Han, Jing Yang, Haoxin Wang, Xinyan Zhang, Yong Zhang, Yuanpeng Gao
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2025-12-01
Series:	Veterinary Research
Assuntos:	Dairy cows Mycobacterium tuberculosis SP110 alternative splicing
Acceso en liña:	https://doi.org/10.1186/s13567-025-01644-3
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