The FERM and PDZ domain-containing protein tyrosine phosphatases, PTPN4 and PTPN3, are both dispensable for T cell receptor signal transduction.

PTPN3 and PTPN4 are two closely-related non-receptor protein tyrosine phosphatases (PTP) that, in addition to a PTP domain, contain FERM (Band 4.1, Ezrin, Radixin, and Moesin) and PDZ (PSD-95, Dlg, ZO-1) domains. Both PTP have been implicated as negative-regulators of early signal transduction throu...

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Ngā kaituhi matua:	Timothy J Bauler, Wiljan J A J Hendriks, Philip D King
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Public Library of Science (PLoS) 2008-01-01
Rangatū:	PLoS ONE
Urunga tuihono:	http://europepmc.org/articles/PMC2602985?pdf=render
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