The binding affinity of PTPN13’s tandem PDZ2/3 domain is allosterically modulated
Abstract Background Protein tyrosine phosphatase PTPN13, also known as PTP-BL in mice, is a large multi-domain non-transmembrane scaffolding protein with a molecular mass of 270 kDa. It is involved in the regulation of several cellular processes such as cytokinesis and actin-cytoskeletal rearrangeme...
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2019-07-01
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| coleção: | BMC Molecular and Cell Biology |
| Assuntos: | |
| Acesso em linha: | http://link.springer.com/article/10.1186/s12860-019-0203-6 |
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