Limitation of site-stratified cox regression analysis in survival data: a cautionary tale of the PANAMO phase III randomized, controlled study in critically ill COVID-19 patients

Abstract Current guidelines tend to focus on a p-value threshold of a pre-specified primary endpoint tested in randomized controlled clinical trials to determine a treatment effect for a specific drug. However, a p-value does not always provide evidence on the treatment effect of a drug, especially...

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Váldodahkkit:	Christian E. Sandrock, Peter X. K. Song
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	BMC 2024-12-01
Ráidu:	Trials
Fáttát:	Cox proportional hazards regression Survival analysis Vilobelimab PANAMO COVID-19
Liŋkkat:	https://doi.org/10.1186/s13063-024-08679-5
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