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Limitation of site-stratified cox regression analysis in survival data: a cautionary tale of the PANAMO phase III randomized, controlled study in critically ill COVID-19 patients

Abstract Current guidelines tend to focus on a p-value threshold of a pre-specified primary endpoint tested in randomized controlled clinical trials to determine a treatment effect for a specific drug. However, a p-value does not always provide evidence on the treatment effect of a drug, especially...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Christian E. Sandrock, Peter X. K. Song
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BMC 2024-12-01
Saila:Trials
Gaiak:
Sarrera elektronikoa:https://doi.org/10.1186/s13063-024-08679-5
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