Quantitative gradient recalled echo (qGRE) MRI enables in vivo measurement of pre-atrophic neurodegeneration in a mouse model of Alzheimer's disease

Robust methods are needed for preclinical evaluation of novel Alzheimer Disease (AD) therapies to accelerate drug discovery. Quantitative Gradient Recalled Echo (qGRE) MRI has shown promise to provide insight into neurodegeneration in AD prior to atrophy development in humans, highlighting areas of...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Michal R. Tomaszewski, Alexander L. Sukstanskii, Hyking Haley, Xiangjun Meng, Corin O. Miller, Dmitriy A. Yablonskiy
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2024-09-01
Schriftenreihe:	NeuroImage
Schlagworte:	MRI Alzheimer's disease Tg4510 Neurodegeneration Neuronal density QGRE
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S105381192400291X
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!