Optimization of self-nanoemulsifying formulations for weakly basic lipophilic drugs: role of acidification and experimental design

ABSTRACT Formulators face great challenges in adopting systematic approaches for designing self-nanoemulsifying formulations (SNEFs) for different drug categories. In this study, we aimed to build-up an advanced SNEF development framework for weakly basic lipophilic drugs, such as cinnarizine (CN)....

Descrición completa

Detalles Bibliográficos

Principais autores:	Ahmad Abdul-Wahhab Shahba, Kazi Mohsin, Fars Kaed Alanazi, Sayed Ibrahim Abdel-Rahman
Formato:	Artigo
Idioma:	Inglês
Publicado:	Universidade de São Paulo, Faculdade de Ciências Farmacêuticas
Series:	Brazilian Journal of Pharmaceutical Sciences
Assuntos:	Self-nanoemulsifying formulations/solubility Cinnarizine/lipophilic drugs Acidification/experimental design Solubility enhancement.
Acceso en liña:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502016000400653&lng=en&tlng=en
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!