Background malaria incidence and parasitemia during the three-dose RTS,S/AS01 vaccination series do not reduce magnitude of antibody response nor efficacy against the first case of malaria

Abstract Background RTS,S/AS01 has been recommended by WHO for widespread implementation in medium to high malaria transmission settings. Previous analyses have noted lower vaccine efficacies in higher transmission settings, possibly due to the more rapid development of naturally acquired immunity i...

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Autori principali:	Griffin J Bell, Stephaney Gyaase, Varun Goel, Bright Adu, Benedicta Mensah, Paulin Essone, David Dosoo, Musah Osei, Karamoko Niare, Kenneth Wiru, Katerina Brandt, Michael Emch, Anita Ghansah, Kwaku Poku Asante, Tisungane Mvalo, Selidji Todagbe Agnandji, Jonathan J Juliano, Jeffrey A Bailey
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2023-10-01
Serie:	BMC Infectious Diseases
Soggetti:	Vaccine Africa Geographic information system GIS Immunology Delayed Malaria
Accesso online:	https://doi.org/10.1186/s12879-023-08699-7
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