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Background malaria incidence and parasitemia during the three-dose RTS,S/AS01 vaccination series do not reduce magnitude of antibody response nor efficacy against the first case of malaria

Abstract Background RTS,S/AS01 has been recommended by WHO for widespread implementation in medium to high malaria transmission settings. Previous analyses have noted lower vaccine efficacies in higher transmission settings, possibly due to the more rapid development of naturally acquired immunity i...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Griffin J Bell, Stephaney Gyaase, Varun Goel, Bright Adu, Benedicta Mensah, Paulin Essone, David Dosoo, Musah Osei, Karamoko Niare, Kenneth Wiru, Katerina Brandt, Michael Emch, Anita Ghansah, Kwaku Poku Asante, Tisungane Mvalo, Selidji Todagbe Agnandji, Jonathan J Juliano, Jeffrey A Bailey
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2023-10-01
Schriftenreihe:BMC Infectious Diseases
Schlagworte:
Vaccine
Africa
Geographic information system
GIS
Immunology
Delayed Malaria
Online-Zugang:https://doi.org/10.1186/s12879-023-08699-7
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