Stem-like memory-T maintenance and differentiation into tissue-resident T cells sustain chronic graft-versus-host disease in mice

Abstract Pathogenic CD4+ memory T cells (Tm) sustain chronic inflammation, but mechanisms remain undefined. Here, we identify four donor-type CD4+ Tm subsets in the target tissues of autoimmune-like chronic graft-versus-host disease in mice: Ly108+CD69− stem-like memory T cells (Tsm), Ly108+CD69+ re...

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Egile Nagusiak:	Xiaohui Kong, Bixin Wang, Xiwei Wu, Hyejin Cho, Weijia Fu, Qinjian Li, Rong Zhang, Ubaydah Nasri, Moqian Zheng, Alyssa Wu, Hanjun Qin, Joey H. Li, Raju Pillai, Timothy E. O’Sullivan, Ryotaro Nakamura, Paul J. Martin, Yuanzhong Chen, Defu Zeng
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Nature Portfolio 2026-02-01
Saila:	Nature Communications
Sarrera elektronikoa:	https://doi.org/10.1038/s41467-026-69975-z
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