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Corticosteroids for sepsis and septic shock: a meta-analysis of 18 RCTs with dose-stratified and fludrocortisone subgroup evaluation

Abstract Background The therapeutic benefit of corticosteroids in managing sepsis and septic shock remains controversial, particularly concerning optimal dosing strategies and the role of adjunctive fludrocortisone. Recent large-scale trials and updated guidelines underscore the need for a dose-stra...

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Principais autores: Lv Ruyuan, Shen Zhangshun, Li Hongling, Su Jianling
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2025-10-01
Series:BMC Anesthesiology
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Acceso en liña:https://doi.org/10.1186/s12871-025-03388-1
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