Corticosteroids for sepsis and septic shock: a meta-analysis of 18 RCTs with dose-stratified and fludrocortisone subgroup evaluation

Abstract Background The therapeutic benefit of corticosteroids in managing sepsis and septic shock remains controversial, particularly concerning optimal dosing strategies and the role of adjunctive fludrocortisone. Recent large-scale trials and updated guidelines underscore the need for a dose-stra...

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Autors principals:	Lv Ruyuan, Shen Zhangshun, Li Hongling, Su Jianling
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2025-10-01
Col·lecció:	BMC Anesthesiology
Matèries:	Sepsis Septic shock Corticosteroids Hydrocortisone Fludrocortisone Meta-analysis
Accés en línia:	https://doi.org/10.1186/s12871-025-03388-1
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