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Dorsomorphin attenuates ABCG2-mediated multidrug resistance in colorectal cancer

Colorectal cancer is a common malignant tumor with high mortality, for which chemotherapy resistance is one of the main reasons. The high expression of ABCG2 in the cancer cells and expulsion of anticancer drugs directly cause multidrug resistance (MDR). Therefore, the development of new ABCG2 inhib...

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Huvudupphov: Xiao-Peng Li, Liang-Qi Cao, Ze-Zhong Yu, Ke He, Peng-Bo Ding, Ji-Sheng Li, Yi-Yao Shan, Yu-Bin Su, Zhong-Min Yuan, Zhi Shi
Materialtyp: Artigo
Språk:Inglês
Utgiven: Frontiers Media S.A. 2024-05-01
Serie:Frontiers in Pharmacology
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Länkar:https://www.frontiersin.org/articles/10.3389/fphar.2024.1393693/full
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