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Collagenase-Responsive Hydrogel Loaded with GSK2606414 Nanoparticles for Periodontitis Treatment through Inhibiting Inflammation-Induced Expression of PERK of Periodontal Ligament Stem Cells

GSK2606414 is a new, effective, highly selective PERK inhibitor with adenosine-triphosphate-competitive characteristics. It can inhibit endoplasmic reticulum stress and has the possibility of treating periodontitis. However, owing to its strong hydrophobicity and side effects, highly efficient pharm...

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Autori principali: Yuchen Zhou, Jie Liu, Peng Xue, Jianjun Zhang
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2023-10-01
Serie:Pharmaceutics
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Accesso online:https://www.mdpi.com/1999-4923/15/10/2503
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