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Radiation-induced ferroptosis via liposomal delivery of 7-Dehydrocholesterol

Abstract Background Ferroptosis is an emerging cell death mechanism characterized by uncontrolled lipid peroxidation. However, selectively inducing ferroptosis in cancer cells remains a challenge. Methods We explore an approach that enables ferroptosis induction through external radiation. The key c...

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Автори: Jianwen Li, Shuyue Zhan, Wei Yang, He Zhang, Xinrui Ma, Fanghui Chen, Amy Li, Pakteema Tong, Fangchao Jiang, Zhengwei Cao, Ian Delahunty, Jiayi Wang, Yufei Wu, Zhi Liu, Zibo Li, Yong Teng, Libin Xu, Jin Xie
Формат: Artigo
Мова:Inglês
Опубліковано: BMC 2025-03-01
Серія:Journal of Nanobiotechnology
Предмети:
Liposomes
7-dehydrocholesterol
Radiosensitizer
Lipid peroxidation
Ferroptosis
Онлайн доступ:https://doi.org/10.1186/s12951-025-03303-3
Теги: Додати тег
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