Radiation-induced ferroptosis via liposomal delivery of 7-Dehydrocholesterol

Abstract Background Ferroptosis is an emerging cell death mechanism characterized by uncontrolled lipid peroxidation. However, selectively inducing ferroptosis in cancer cells remains a challenge. Methods We explore an approach that enables ferroptosis induction through external radiation. The key c...

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Principais autores:	Jianwen Li, Shuyue Zhan, Wei Yang, He Zhang, Xinrui Ma, Fanghui Chen, Amy Li, Pakteema Tong, Fangchao Jiang, Zhengwei Cao, Ian Delahunty, Jiayi Wang, Yufei Wu, Zhi Liu, Zibo Li, Yong Teng, Libin Xu, Jin Xie
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2025-03-01
Serija:	Journal of Nanobiotechnology
Teme:	Liposomes 7-dehydrocholesterol Radiosensitizer Lipid peroxidation Ferroptosis
Online dostop:	https://doi.org/10.1186/s12951-025-03303-3
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