Mendelian randomization reveals interactions of the blood proteome and immunome in mitral valve prolapse
Abstract Background Mitral valve prolapse (MVP) is a common heart disorder characterized by an excessive production of proteoglycans and extracellular matrix in mitral valve leaflets. Large-scale genome-wide association study (GWAS) underlined that MVP is heritable. The molecular underpinnings of th...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Portfolio
2024-06-01
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| coleção: | Communications Medicine |
| Acesso em linha: | https://doi.org/10.1038/s43856-024-00530-x |
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