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Smart stimuli-responsive carrier-free nanoassembly of SN38 prodrug as efficient chemotherapeutic nanomedicine

The compound 7-ethyl-10-hydroxy-camptothecin (SN38) is a broad-spectrum antitumor agent whose applications are greatly limited by its poor solubility. Therefore, irinotecan, the hydrophilic derived prodrug of SN38, has been developed as the commercial formulation Campto ® for colorectal cancer. How...

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Principais autores: Guanting Li, Qianhui Jin, Fengli Xia, Shuwen Fu, Xuanbo Zhang, Hongying Xiao, Chutong Tian, Qingzhi Lv, Jin Sun, Zhonggui He, Bingjun Sun
Formato: Artigo
Idioma:Inglês
Publicado em: Compuscript Ltd 2023-01-01
Colecção:Acta Materia Medica
Acesso em linha:https://www.scienceopen.com/hosted-document?doi=10.15212/AMM-2023-0003
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