The degradation of TGR5 mediated by Smurf1 contributes to diabetic nephropathy
Summary: The multiple roles of TGR5 in the regulation of glucose metabolism, inflammation, and oxidative stress have drawn attention as therapeutic candidates for diabetes-related kidney disease. However, diabetes induces downregulation of renal TGR5 protein expression, and the regulatory mechanisms...
Salvato in:
| Autori principali: | , , , , , , , , |
|---|---|
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2023-08-01
|
| Serie: | Cell Reports |
| Soggetti: | |
| Accesso online: | http://www.sciencedirect.com/science/article/pii/S2211124723008628 |
| Tags: |
Nessun Tag, puoi essere il primo ad aggiungerne!!
|