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A Novel Function of Mitochondrial Phosphoenolpyruvate Carboxykinase as a Regulator of Inflammatory Response in Kupffer Cells

Background: There has been a recent appreciation that some metabolic enzymes can profoundly influence the nature of the immune response produced in macrophages. However, the role of mitochondrial phosphoenolpyruvate carboxykinase (PCK2) in immune response remains unknown. This study aims to investig...

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Principais autores: Haibo Dong, Yue Feng, Yang Yang, Yun Hu, Yimin Jia, Shu Yang, Nannan Zhao, Ruqian Zhao
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021-12-01
Serier:Frontiers in Cell and Developmental Biology
Fag:
inflammation
Pck2
protein phosphorylation
Kupffer cell
mitochondrial dysfunction
Online adgang:https://www.frontiersin.org/articles/10.3389/fcell.2021.726931/full
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