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Phosphoenolpyruvate carboxykinase in cell metabolism: Roles and mechanisms beyond gluconeogenesis

Background: Phosphoenolpyruvate carboxykinase (PCK) has been almost exclusively recognized as a critical enzyme in gluconeogenesis, especially in the liver and kidney. Accumulating evidence has shown that the enhanced activity of PCK leads to increased glucose output and exacerbation of diabetes, wh...

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Principais autores: Shuo Yu, Simin Meng, Meixiang Xiang, Hong Ma
פורמט: Artigo
שפה:Inglês
יצא לאור: Elsevier 2021-11-01
סדרה:Molecular Metabolism
נושאים:
Phosphoenolpyruvate carboxykinase (PCK)
Gluconeogenesis
Glyceroneogenesis
Transcription regulation
Posttranscription regulation
Epigenetic regulation
גישה מקוונת:http://www.sciencedirect.com/science/article/pii/S2212877821001022
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