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gRNA Design: How Its Evolution Impacted on CRISPR/Cas9 Systems Refinement

Over the past decade, genetic engineering has witnessed a revolution with the emergence of a relatively new genetic editing tool based on RNA-guided nucleases: the CRISPR/Cas9 system. Since the first report in 1987 and characterization in 2007 as a bacterial defense mechanism, this system has garner...

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Bibliografische gegevens
Hoofdauteurs: Cristofer Motoche-Monar, Julián E. Ordoñez, Oscar Chang, Fernando A. Gonzales-Zubiate
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI AG 2023-11-01
Reeks:Biomolecules
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Online toegang:https://www.mdpi.com/2218-273X/13/12/1698
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