gRNA Design: How Its Evolution Impacted on CRISPR/Cas9 Systems Refinement
Over the past decade, genetic engineering has witnessed a revolution with the emergence of a relatively new genetic editing tool based on RNA-guided nucleases: the CRISPR/Cas9 system. Since the first report in 1987 and characterization in 2007 as a bacterial defense mechanism, this system has garner...
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| Principais autores: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
MDPI AG
2023-11-01
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| Serija: | Biomolecules |
| Teme: | |
| Online dostop: | https://www.mdpi.com/2218-273X/13/12/1698 |
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