Differential regional expression patterns of α-synuclein, TNF-α, and IL-1β; and variable status of dopaminergic neurotoxicity in mouse brain after Paraquat treatment

<p>Abstract</p> <p>Background</p> <p>Paraquat (1, 1-dimethyl-4, 4-bipyridium dichloride; PQ) causes neurotoxicity, especially dopaminergic neurotoxicity, and is a supposed risk factor for Parkinson's disease (PD). However, the cellular and molecular mechanisms of PQ-induced neurodegeneration are far...

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Hlavní autoři:	Mitra Soham, Chakrabarti Nilkanta, Bhattacharyya Arindam
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2011-11-01
Edice:	Journal of Neuroinflammation
Témata:	Paraquat α-synuclein tyrosine hydroxylase tumor necrosis factor-α interleukin-1β substantia nigra frontal cortex, hippocampus
On-line přístup:	http://www.jneuroinflammation.com/content/8/1/163
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