Role of chitinase-3-like protein 1 in liver diseases: A comprehensive review

Chitinase-3-like protein 1 (CHI3L1) is part of the glycoside hydrolase family 18. Despite lacking enzymatic activity, its unique structure allows it to bind to ligands, altering its steric configuration to mediate cell proliferation, inflammation, fibrosis, and carcinogenesis. In liver disease, CHI3...

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Detalhes bibliográficos

Principais autores:	Chao Tian, Shizhou Deng, Ming Yang, Baochen Bai, Lai Wei
Formato:	Artigo
Idioma:	Inglês
Publicado em:	KeAi Communications Co., Ltd. 2025-11-01
coleção:	Genes and Diseases
Assuntos:	Chitinase-3-like protein 1 Hepatic fibrosis Hepatocellular carcinoma Liver disease biomarker Non-alcoholic steatohepatitis Signaling pathways
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2352304225001424
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