Structural insight into the tetramerization of an iterative ketoreductase siam through aromatic residues in the interfaces.

In the biosynthesis of polyketides, ketoreductases (KRs) are an important group of enzymes that determine the chiralities of the carbon backbones. SiaM is a special member of this group that can recognize substrates with different lengths and can be used iteratively. Here we report the crystal struc...

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Ngā kaituhi matua:	Hua Wang, Huaidong Zhang, Yi Zou, Yanling Mi, Shuangjun Lin, Zhixiong Xie, Yunjun Yan, Houjin Zhang
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Public Library of Science (PLoS) 2014-01-01
Rangatū:	PLoS ONE
Urunga tuihono:	http://europepmc.org/articles/PMC4046962?pdf=render
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!