A multifunctional ICAM1-directed MnO₂@ZIF8 nanoplatform with Tanshinone IIA synergistically reverses senescence and restores alveolar regeneration in septic lung injury

Abstract Sepsis-induced acute lung injury (ALI) is characterized by severe oxidative stress and senescence of alveolar type II epithelial cells (AECⅡ), yet effective therapies capable of reversing these pathological processes remain lacking. We developed a multifunctional ICAM1-targeted MnO2@ZIF8 na...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Shan Lin, Xuefeng Ding, Xin Dang, Dachen Luo, Dan Cao, Zonglian Gong, Qingyuan Zhan
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2026-04-01
Serie:	Journal of Nanobiotechnology
Soggetti:	Sepsis Acute Lung Injury Alveolar Epithelial Cells Type II Senescence Nanozyme
Accesso online:	https://doi.org/10.1186/s12951-026-04362-w
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!