CD8+-T Cells With Specificity for a Model Antigen in Cardiomyocytes Can Become Activated After Transverse Aortic Constriction but Do Not Accelerate Progression to Heart Failure

Heart failure due to pressure overload is frequently associated with inflammation. In addition to inflammatory responses of the innate immune system, autoimmune reactions of the adaptive immune system appear to be triggered in subgroups of patients with heart failure as demonstrated by the presence...

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Hlavní autoři:	Carina Gröschel, André Sasse, Sebastian Monecke, Charlotte Röhrborn, Leslie Elsner, Michael Didié, Verena Reupke, Gertrude Bunt, Andrew H. Lichtman, Karl Toischer, Wolfram-Hubertus Zimmermann, Gerd Hasenfuß, Ralf Dressel
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2018-11-01
Edice:	Frontiers in Immunology
Témata:	autoimmunity autoantigen pressure overload cytotoxic T cells adoptive transfer transgenic T cell receptor
On-line přístup:	https://www.frontiersin.org/article/10.3389/fimmu.2018.02665/full
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