CD8+-T Cells With Specificity for a Model Antigen in Cardiomyocytes Can Become Activated After Transverse Aortic Constriction but Do Not Accelerate Progression to Heart Failure

Heart failure due to pressure overload is frequently associated with inflammation. In addition to inflammatory responses of the innate immune system, autoimmune reactions of the adaptive immune system appear to be triggered in subgroups of patients with heart failure as demonstrated by the presence...

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Detalles Bibliográficos

Principais autores:	Carina Gröschel, André Sasse, Sebastian Monecke, Charlotte Röhrborn, Leslie Elsner, Michael Didié, Verena Reupke, Gertrude Bunt, Andrew H. Lichtman, Karl Toischer, Wolfram-Hubertus Zimmermann, Gerd Hasenfuß, Ralf Dressel
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2018-11-01
Series:	Frontiers in Immunology
Assuntos:	autoimmunity autoantigen pressure overload cytotoxic T cells adoptive transfer transgenic T cell receptor
Acceso en liña:	https://www.frontiersin.org/article/10.3389/fimmu.2018.02665/full
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