Genetic Association Reveals Protection against Recurrence of <italic toggle="yes">Clostridium difficile</italic> Infection with Bezlotoxumab Treatment

ABSTRACT Bezlotoxumab is a human monoclonal antibody against Clostridium difficile toxin B, indicated to prevent recurrence of C. difficile infection (rCDI) in high-risk adults receiving antibacterial treatment for CDI. An exploratory genome-wide association study investigated whether human genetic...

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Autores principales:	Judong Shen, Devan V. Mehrotra, Mary Beth Dorr, Zhen Zeng, Junhua Li, Xun Xu, David Nickle, Emily R. Holzinger, Aparna Chhibber, Mark H. Wilcox, Rebecca L. Blanchard, Peter M. Shaw
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology 2020-06-01
Colección:	mSphere
Materias:	Clostridium difficile antibacterials bezlotoxumab genomics
Acceso en línea:	https://journals.asm.org/doi/10.1128/mSphere.00232-20
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