Intrinsic Toxin-Derived Peptides Destabilize and Inactivate <italic toggle="yes">Clostridium difficile</italic> TcdB
ABSTRACT Clostridium difficile infection (CDI) is a major cause of hospital-associated, antibiotic-induced diarrhea, which is largely mediated by the production of two large multidomain clostridial toxins, TcdA and TcdB. Both toxins coordinate the action of specific domains to bind receptors, enter...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
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American Society for Microbiology
2017-07-01
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| Serie: | mBio |
| Soggetti: | |
| Accesso online: | https://journals.asm.org/doi/10.1128/mBio.00503-17 |
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