Resolving the Haplotype Complexity of Colorectal Cancer Genomes with Droplet Barcode Sequencing

Precision medicine is increasingly applied in the cancer clinic, adapting treatment to genomic alterations of the tumor. However, whether alterations disrupt the function of a protein can depend on if both alleles of a gene are altered. While massively parallel sequencing technologies can identify s...

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Autors principals:	Humam Siga, Pontus Höjer, Parham Pourbozorgi, Hooman Aghelpasand, Max Käller, Johan Hartman, Cecilia Williams, Afshin Ahmadian
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2026-05-01
Col·lecció:	Life
Matèries:	cancer genomics colorectal cancer CRC linked-reads haplotyping droplet barcode sequencing
Accés en línia:	https://www.mdpi.com/2075-1729/16/6/874
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