MELK prevents radiofrequency ablation-induced immunogenic cell death and antitumor immune response by stabilizing FABP5 in hepatocellular malignancies

Abstract Background Radiofrequency ablation (RFA) is an efficient treatment with unlimited potential for liver cancer that can effectively reduce patient mortality. Understanding the biological process related with RFA treatment is important for improving treatment strategy. This study aimed to iden...

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Bibliografski detalji

Glavni autori:	Bu-Fu Tang, Wang-Ting Xu, Shi-Ji Fang, Jin-Yu Zhu, Rong-Fang Qiu, Lin Shen, Yang Yang, Qiao-You Weng, Ya-Jie Wang, Jia-Yi Ding, Xiao-Jie Zhang, Wei-Qian Chen, Li-Yun Zheng, Jing-Jing Song, Biao Chen, Zhong-Wei Zhao, Min-Jiang Chen, Jian-Song Ji
Format:	Artigo
Jezik:	Inglês
Izdano:	KeAi Communications Co., Ltd. 2025-01-01
Serija:	Military Medical Research
Teme:	Radiofrequency ablation Liver cancer Maternal embryonic leucine zipper kinase (MELK) Fatty acid-binding protein 5 (FABP5) Immune microenvironment Nanoparticles
Online pristup:	https://doi.org/10.1186/s40779-024-00588-7
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