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The main steps of TCR signalingNegative times negative equals positive, THEMIS sets the rule on thymic selection and peripheral T cell responses

The activity of T cells is finely controlled by a set of negative regulators of T-cell antigen receptor (TCR)-mediated signaling. However, how those negative regulators are themselves controlled to prevent ineffective TCR-mediated responses remain poorly understood. Thymocyte-expressed molecule invo...

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Détails bibliographiques
Auteurs principaux: Suzanne Mélique, Cui Yang, Renaud Lesourne
Format: Artigo
Langue:Inglês
Publié: Elsevier 2022-04-01
Collection:Biomedical Journal
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Accès en ligne:http://www.sciencedirect.com/science/article/pii/S2319417022000373
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