In vitro and in vivo activities of scutellarein, a novel polyphosphate kinase 1 inhibitor against Acinetobacter baumannii infection

Abstract Background Inorganic polyphosphate (polyP)-targeted polyphosphate kinase 1 (PPK1) has attracted much attention by virtue of its importance in bacterial pathogenicity and persistence, as well as its exclusive presence in microorganisms. However, only very few drugs have been found to be effi...

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Hlavní autoři:	Yuping Song, Hongfa Lv, Lei Xu, Zhiying Liu, Jianfeng Wang, Tianqi Fang, Xuming Deng, Yonglin Zhou, Dan Li
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2024-10-01
Edice:	Microbial Cell Factories
Témata:	A. baumannii Polyphosphate kinase 1 Polyphosphate Scutellarein Pathogenicity Persistence
On-line přístup:	https://doi.org/10.1186/s12934-024-02540-9
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