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Validation of an LC–HRMS Method for Quantifying Indoxyl Sulfate and <i>p</i>-Cresyl Sulfate in Human Serum

Accurate quantification of indoxyl sulfate (IndS) and <i>p</i>-cresyl sulfate (pCS) is essential for understanding their role in chronic kidney disease (CKD) progression and for developing strategies to mitigate their harmful effects, including cardiovascular morbidity and renal fibrosis. Advances i...

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Principais autores: María Rodríguez-García, Irene Martínez, Irene Aliart, Jaime I. Sainz de Medrano, Nayra Rico, Víctor Joaquín Escudero-Saiz, Francisco Maduell, Manuel Morales-Ruiz, Gregori Casals
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2025-02-01
coleção:Molecules
Assuntos:
chronic kidney disease
uremic toxins
high-resolution mass spectrometry
micro-liquid chromatography
hemodiafiltration
metabolomics
Acesso em linha:https://www.mdpi.com/1420-3049/30/4/782
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