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Upregulation of the Adhesin Gene <italic toggle="yes">EPA1</italic> Mediated by <italic toggle="yes">PDR1</italic> in <named-content content-type="genus-species">Candida glabrata</named-content> Leads to Enhanced Host Colonization

ABSTRACT Candida glabrata is the second most common Candida species causing disseminated infection, after C. albicans. C. glabrata is intrinsically less susceptible to the widely used azole antifungal drugs and quickly develops secondary resistance. Resistance typically relies on drug efflux with tr...

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Principais autores: Luis A. Vale-Silva, Beat Moeckli, Riccardo Torelli, Brunella Posteraro, Maurizio Sanguinetti, Dominique Sanglard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016-04-01
coleção:mSphere
Assuntos:
Candida
drug resistance
adherence
fungus-host interactions
Acesso em linha:https://journals.asm.org/doi/10.1128/mSphere.00065-15
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