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Upregulation of the Adhesin Gene <italic toggle="yes">EPA1</italic> Mediated by <italic toggle="yes">PDR1</italic> in <named-content content-type="genus-species">Candida glabrata</named-content> Leads to Enhanced Host Colonization

ABSTRACT Candida glabrata is the second most common Candida species causing disseminated infection, after C. albicans. C. glabrata is intrinsically less susceptible to the widely used azole antifungal drugs and quickly develops secondary resistance. Resistance typically relies on drug efflux with tr...

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Principais autores: Luis A. Vale-Silva, Beat Moeckli, Riccardo Torelli, Brunella Posteraro, Maurizio Sanguinetti, Dominique Sanglard
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016-04-01
Serier:mSphere
Fag:
Candida
drug resistance
adherence
fungus-host interactions
Online adgang:https://journals.asm.org/doi/10.1128/mSphere.00065-15
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