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Binding of HMGN proteins to cell specific enhancers stabilizes cell identity

HMGN1 and HMGN2 are ubiquitous nucleosome binding proteins. Here the authors provide evidence that HMGN proteins preferentially localize to chromatin regulatory sites to modulate the plasticity of the epigenetic landscape, proposing that HGMNs stabilize, rather than determine, cell identity.

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Detaylı Bibliyografya
Asıl Yazarlar: Bing He, Tao Deng, Iris Zhu, Takashi Furusawa, Shaofei Zhang, Wei Tang, Yuri Postnikov, Stefan Ambs, Caiyi Cherry Li, Ferenc Livak, David Landsman, Michael Bustin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Portfolio 2018-12-01
Seri Bilgileri:Nature Communications
Online Erişim:https://doi.org/10.1038/s41467-018-07687-9
Etiketler: Etiketle
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