Structural insight into Okazaki fragment maturation mediated by PCNA-bound FEN1 and RNaseH2
Abstract PCNA is a master coordinator of many DNA-metabolic events. During DNA replication, the maturation of Okazaki fragments involves at least four DNA enzymes, all of which contain PCNA-interacting motifs. However, the temporal relationships and functional modulations between these PCNA-binding...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer Nature
2024-11-01
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| Col·lecció: | The EMBO Journal |
| Matèries: | |
| Accés en línia: | https://doi.org/10.1038/s44318-024-00296-x |
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