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ALDOC and PGK1 coordinately induce glucose metabolism reprogramming and promote development of colorectal cancer

Abstract Colorectal cancer (CRC) remains a significant health challenge globally, demanding a comprehensive understanding of its molecular underpinnings for effective management. In this study, we investigated the role of Aldolase C (ALDOC), a glycolytic enzyme, in CRC pathogenesis. Transcriptomic a...

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Huvudupphov: Liyong Huang, Yixin Tong, Xu Li, Wei Wang, Zhen Wang, Bingchen Chen, Jifu E., Ruzhen Zhou, Hantao Wang, Jinghu He
Materialtyp: Artigo
Språk:Inglês
Utgiven: BMC 2025-06-01
Serie:Molecular Medicine
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Länkar:https://doi.org/10.1186/s10020-025-01252-z
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