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ALDOC and PGK1 coordinately induce glucose metabolism reprogramming and promote development of colorectal cancer

Abstract Colorectal cancer (CRC) remains a significant health challenge globally, demanding a comprehensive understanding of its molecular underpinnings for effective management. In this study, we investigated the role of Aldolase C (ALDOC), a glycolytic enzyme, in CRC pathogenesis. Transcriptomic a...

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Principais autores: Liyong Huang, Yixin Tong, Xu Li, Wei Wang, Zhen Wang, Bingchen Chen, Jifu E., Ruzhen Zhou, Hantao Wang, Jinghu He
פורמט: Artigo
שפה:Inglês
יצא לאור: BMC 2025-06-01
סדרה:Molecular Medicine
נושאים:
Colorectal cancer
ALDOC
PGK1
Glycolysis
Molecular mechanism
גישה מקוונת:https://doi.org/10.1186/s10020-025-01252-z
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