Adiposity, metabolites and endometrial cancer risk: inference from combinations of Mendelian randomization and observational analyses

Abstract Introduction The associations between excess adiposity and endometrial cancer (EC) risk may be mediated by altered metabolic profiles. Here, we triangulated evidence from observational and Mendelian randomisation (MR) analyses to investigate the relationship between adiposity traits, circul...

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Autors principals:	Matthew A. Lee, Vanessa Y. Tan, Dimitri J. Pournaras, Sabrina Wang, Laure Dossus, Marc J. Gunter, Kaitlin H. Wade, Laura J. Corbin, Nicholas J. Timpson
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2025-10-01
Col·lecció:	BMC Cancer
Matèries:	Adiposity Metabolites Endometrial cancer Mendelian randomization
Accés en línia:	https://doi.org/10.1186/s12885-025-14756-y
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