L-NAME releases nitric oxide and potentiates subsequent nitroglycerin-mediated vasodilation
L-NG-Nitro arginine methyl ester (L-NAME) has been widely applied for several decades in both basic and clinical research as an antagonist of nitric oxide synthase (NOS). Herein, we show that L-NAME slowly releases NO from its guanidino nitro group. Daily pretreatment of rats with L-NAME potentiated...
Guardat en:
| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2019-09-01
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| Col·lecció: | Redox Biology |
| Accés en línia: | http://www.sciencedirect.com/science/article/pii/S2213231719303945 |
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