Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

ABSTRACT Neuropathic pain (NPP) is a critical clinical challenge with limited therapeutic options. While neuronal mechanisms have been extensively studied, the contribution of oligodendrocyte (OL) homeostasis to NPP pathogenesis is poorly understood. Here, we show that chronic constriction injury (C...

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Detalhes bibliográficos

Principais autores:	Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2026-07-01
coleção:	Advanced Science
Assuntos:	c‐Myc myelin neuropathic pain oligodendrocyte PDK1 SOX10
Acesso em linha:	https://doi.org/10.1002/advs.202516426
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